CD44 anticorps

N° du produit ABIN6297698

L’anticorps Souris Monoclonal anti-CD44 a été validé pour IHC. Il convient pour détecter CD44 dans des échantillons de Humain, Babouin et Green Monkey.

Aperçu rapide pour CD44 anticorps (ABIN6297698)

Antigène: CD44

Reactivité: Humain, Babouin, Green Monkey

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD44 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-CD44 anticorps

Fonction: Mouse anti-Human/Baboon/Green Monkey HCAM Antibody CD44 [IHC only]

Specificité: Cell surface

Purification: Stimulated human leukocytes were used as the immunogen for this CD44 / HCAM antibody.

Immunogène: Stimulated human leukocytes were used as the immunogen for this CD44 / HCAM antibody.

Information d'application

Indications d'application: Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Buffer: Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur CD44

Antigène: CD44

Autre désignation: CD44 antigen

Sujet:

Target Description: This antibody recognizes a cell surface glycoprotein of 80-95 kDa, called CD44, or HCAM, on lymphocytes, monocytes, and granulocytes (Leucocyte Typing Workshop V). Its epitope is resistant to digestion by trypsin and chymotrypsin. The CD44 family of glycoproteins exists in a number of variant isoforms, the most common being the standard 85-95 kDa or hematopoietic variant (CD44-s). Higher molecular weight isoforms are described in epithelial cells (CD44-v), which are believed to function in intercellular adhesion and stromal binding. HCAM antibody immunostaining is commonly used for the discrimination of urothelial transitional cell carcinoma in-situ from non-neoplastic changes in the urothelium.

Gene Symbol: CD44///LHR///MDU2///MDU3///MIC4

ID gène: 960

UniProt: P16070

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling